HK1 CLIA Kit for Human(Homo sapiens) | EIAab.comHK1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > HK1(Gene name) > Human

HK1 (Gene name),

Hexokinase-1 (Protein name ), HXK1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HK1;

Protein name:

Hexokinase-1;

Alternative:

Hexokinase type I(HK I);Brain form hexokinase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

N/A

Subcellular Location:

Mitochondrion outer membrane Its hydrophobic N-terminal sequence may be involved in membrane binding.

Protein Attributes:

Sequence length:

917

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

917:

AALITAVGVR | LRTEASS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P19367

Pfam:

PF00349

UniGene:

Hs.370365

MIM:

142600

KEGG:

hsa:3098

String:

P19367

STRING:

9606.ENSP00000348697

Uniprot:

P19367

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ELISA Kit for Human Hexokinase-1

Cat.:

E0775b

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96T

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ELISA Kit for Human Hexokinase-1

Cat.:

E0775m

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96T

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ELISA Kit for Human Hexokinase-1

Cat.:

E0775h

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96T

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ELISA Kit for Human Hexokinase-1

Cat.:

E0775r

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96T

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CLIA Kit for Human Hexokinase-1

Cat.:

U0775r

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Looking for manual.

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Packing:

96T

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CLIA Kit for Human Hexokinase-1

Cat.:

U0775b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Hexokinase-1

Cat.:

U0775m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Hexokinase-1

Cat.:

U0775h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Hexokinase-1

Cat.:

P0775Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Hexokinase-1

Cat.:

P0775Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Hexokinase-1

Cat.:

P0775Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Hexokinase-1

Protein for Human Hexokinase-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous."
Nishi S. , Seino S. , Bell G.I.
Biochem. Biophys. Res. Commun.157:937-943(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-776
2.

"Structure of the human hexokinase type I gene and nucleotide sequence of the 5' flanking region."
Ruzzo A. , Andreoni F. , Magnani M.
Biochem. J.331:607-613(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
3.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
5.

"Structure of the 5' region of the human hexokinase type I (HKI) gene and identification of an additional testis-specific HKI mRNA."
Andreoni F. , Ruzzo A. , Magnani M.
Biochim. Biophys. Acta1493:19-26(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-126 (ISOFORM 4);ALTERNATIVE SPLICING
6.

"The erythrocyte-specific hexokinase isozyme (HKR) and the common hexokinase isozyme (HKI) are produced from a single gene by alternate promoters."
Murakami K. , Piomelli S.
Blood90:272-272(1998)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-20 (ISOFORM 2)
7.

Bienvenut W.V. , Waridel P. , Quadroni M.
Submitted (2009-03) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-20; 31-42; 382-396 AND 900-910;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Embryonic kidney.
8.

"Human hexokinase type I microheterogeneity is due to different amino-terminal sequences."
Magnani M. , Serafini G. , Bianchi M. , Casabianca A. , Stocchi V.
J. Biol. Chem.266:502-505(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 11-31 AND 103-120
tissue: Placenta.
9.

"A recombinant human 'mini'-hexokinase is catalytically active and regulated by hexose 6-phosphates."
Magnani M. , Bianchi M. , Casabianca A. , Stocchi V. , Daniele A. , Altruda F. , Ferrone M. , Silengo L.
Biochem. J.285:193-199(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 287-917;VARIANT MET-776
tissue: Placenta.
10.

"Identification of the cDNA for human red blood cell-specific hexokinase isozyme."
Murakami K. , Piomelli S.
Blood89:762-766(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING
11.

"Crystallization and preliminary X-ray analysis of human brain hexokinase."
Aleshin A.E. , Zeng C. , Fromm H.J. , Honatko R.B.
FEBS Lett.391:9-10(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CRYSTALLIZATION
12.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"A mutation in an alternative untranslated exon of hexokinase 1 associated with hereditary motor and sensory neuropathy -- Russe (HMSNR)."
Hantke J. , Chandler D. , King R. , Wanders R.J. , Angelicheva D. , Tournev I. , McNamara E. , Kwa M. , Guergueltcheva V. , Kaneva R. , Baas F. , Kalaydjieva L.
Eur. J. Hum. Genet.17:1606-1614(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HMSNR
14.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"PKCepsilon promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria."
Lau E. , Kluger H. , Varsano T. , Lee K. , Scheffler I. , Rimm D.L. , Ideker T. , Ronai Z.A.
Cell148:543-555(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATF2 AND VDAC1
16.

"The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate."
Aleshin A.E. , Zeng C. , Bourenkov G.P. , Bartunik H.D. , Fromm H.J. , Honzatko R.B.
Structure6:39-50(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 16-914 IN COMPLEX WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE;SUBUNIT
17.

"Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate."
Aleshin A.E. , Zeng C. , Bartunik H.D. , Fromm H.J. , Honzatko R.B.
J. Mol. Biol.282:345-357(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 16-914
18.

"Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control."
Rosano C. , Sabini E. , Rizzi M. , Deriu D. , Murshudov G. , Bianchi M. , Serafini G. , Magnani M. , Bolognesi M.
Structure7:1427-1437(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS) IN COMPLEX WITH AMP-PNP AND MAGNESIUM;SUBUNIT
19.

"Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation."
Aleshin A.E. , Kirby C. , Liu X. , Bourenkov G.P. , Bartunik H.D. , Fromm H.J. , Honzatko R.B.
J. Mol. Biol.296:1001-1015(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH GLUCOSE; GLUCOSE-6-PHOSPHATE AND ADP
20.

"Hexokinase mutations that produce nonspherocytic hemolytic anemia."
Bianchi M. , Magnani M.
Blood Cells Mol. Dis.21:2-8(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HK DEFICIENCY SER-529
21.

"HK Utrecht: missense mutation in the active site of human hexokinase associated with hexokinase deficiency and severe nonspherocytic hemolytic anemia."
van Wijk R. , Rijksen G. , Huizinga E.G. , Nieuwenhuis H.K. , van Solinge W.W.
Blood101:345-347(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HK DEFICIENCY SER-680

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